Here is my suggestion for you. Make fun of yourself. Why? now they can't do it to you. (they can agree, but it is not as satisfying for them so they are a lot less likely to do it)
Or you can make a vlog being like "I was just notified that I am over weight... and I had no idea!" and be completely sincere about it, like the youtube haters just gave you some information you had no idea about.
Honestly the best way to avoid being made fun of, is to beat them to the punch. I am skronny, which sucks as well seeing as its usually the over weight people who make fun of me, because they get made fun of my the people who are normal weight or work out ect. So I just like to make fun of myself saying I can bench at least 10 pounds, and pretend it is an awesome feat.
Unfortunately you can do that or ignore it. If you make a video showing that these comments are getting to you, (by saying stop, or saying it hurts you, or getting angry ect.) they will get worse. So just play fun at it and make it sort of an inside joke for you and your actual subscribers so that when one of those haters comes on and is all " U R FAT LULS!" your subscribers will just be like "Lols U GET THE JOKE!!"
Eventually they will dissapear, haters are just 10 year old kids (usually) who get picked on a lot or just have problems at home and this is how they escape. It's no big deal really.
Good luck with your commentary hate. It's kind of how you tube comments work :/ really annoying too.
Worst case you can just set all of the comments to need approval by you before they are posted on the video.